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Article

Differential Type I IFN-Inducing Abilities of Wild-Type versus Vaccine Strains of Measles Virus

1 Nov 2007

Abstract excerpt

Laboratory adapted and vaccine strains of measles virus (MV) induced type I IFN in infected cells. The wild-type strains in contrast induced it to a far lesser extent. We have investigated the mechanism for this differential type I IFN induction in monocyte-derived dendritic cells infected with representative MV strains. Laboratory adapted strains Nagahata and Edmonston infected monocyte-derived dendritic cells...

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PMID: 17947687
DOI: 10.4049/jimmunol.179.9.6123

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