Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

9 Dec 2014

Abstract excerpt

The type I interferon (IFN) response represents the first line of defence to invading pathogens. Internalized viral ribonucleoproteins (vRNPs) of negative-strand RNA viruses induce an early IFN response by interacting with retinoic acid inducible gene I (RIG-I) and its recruitment to mitochondria. Here we employ three-dimensional stochastic optical reconstruction microscopy (STORM) to visualize incoming influenza...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Influenza Virus Research Studies
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25487526
DOI: 10.1038/ncomms6645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virionsPMID 25487526Read ↗

A two-step mechanism for RIG-I activation by influenza virus mvRNAsSemantic proximity Read ↗

Mini viral RNAs act as innate immune agonists during influenza virus infectionSemantic proximity Read ↗

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate ImmunitySemantic proximity Read ↗

The NS1 protein of influenza B virus binds 5’-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral responseSemantic proximity Read ↗

The NS1 protein of influenza B virus binds 5’-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral responseSemantic proximity Read ↗

Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptorsSemantic proximity Read ↗

Defective Interfering Genomes and the Full-Length Viral Genome Trigger RIG-I After Infection With Vesicular Stomatitis Virus in a Replication Dependent Manner.Semantic proximity Read ↗

RIG-I and MDA-5 Detection of Viral RNA-dependent RNA Polymerase Activity Restricts Positive-Strand RNA Virus ReplicationSemantic proximity Read ↗

Structural insights into the distinctive RNA recognition and therapeutic potentials of RIG‐I‐like receptorsSemantic proximity Read ↗

Defective RNA sensing by RIG-I in severe influenza virus infectionSemantic proximity Read ↗

Signaling through RIG-I and type I interferon receptor: Immune activation by Newcastle disease virus in man versus immune evasion by Ebola virus (Review)Semantic proximity Read ↗

Interactions between the Influenza A Virus RNA Polymerase Components and Retinoic Acid-Inducible Gene ISemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.