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BCCIP regulates homologous recombination by distinct domains and suppresses spontaneous DNA damage

18 Oct 2007

Abstract excerpt

Homologous recombination (HR) is critical for maintaining genome stability through precise repair of DNA double-strand breaks (DSBs) and restarting stalled or collapsed DNA replication forks. HR is regulated by many proteins through distinct mechanisms. Some proteins have direct enzymatic roles in HR reactions, while others act as accessory factors that regulate HR enzymatic activity or coordinate HR with other...

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PMID: 17947333
DOI: 10.1093/nar/gkm732

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