Article
[Influence of ORM1 polymorphism on serum concentration of free nortriptyline].
Yao xue xue bao = Acta pharmaceutica Sinica - 1 Aug 2007
Zhang Che, Tu Zi-Liang, Wang Qi-Bin, Cheng Xiao-Li, Zhang Peng-Hua
Abstract excerpt
To study the effect of alpha1-acid glycoprotein 1 (ORM1) polymorphism on the concentration of free nortriptyline in serum, genotyping analysis was employed in ORM1 by sequencing. Eighteen unrelated male adults were chosen and given a single dose of 25 mg nortriptyline orally, then the blood sampl...
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