Article
Genomic imprinting, growth control and the allocation of nutritional resources: consequences for postnatal life.
Current opinion in endocrinology, diabetes, and obesity - 1 Feb 2007
Charalambous Marika, da Rocha Simão Teixeira, Ferguson-Smith Anne C
Abstract excerpt
PURPOSE OF REVIEW: Genes subject to genomic imprinting are predominantly expressed from one of the two parental chromosomes, are often clustered in the genome, and their activity and repression are epigenetically regulated. The role of imprinted genes in growth control has been apparent since the discovery of imprinting in the early 1980s. RECENT FINDINGS: Drawing from studies in the mouse, we propose three...
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