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Genomic imprinting, growth and maternal–fetal interactions

7 Mar 2018

Abstract excerpt

ABSTRACT In the 1980s, mouse nuclear transplantation experiments revealed that both male and female parental genomes are required for successful development to term (McGrath and Solter, 1983; Surani and Barton, 1983). This non-equivalence of parental genomes is because imprinted genes are predominantly expressed from only one parental chromosome. Uniparental inheritance of these genomic regions causes paediatric...

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PMID: 29514882
DOI: 10.1242/jeb.164517

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