Article
Genomic imprinting--roles and regulation in development.
Endocrine development - 1 Jan 2007
Kelsey Gavin
Abstract excerpt
Genomic imprinting results in the deliberate silencing of alleles, dictated by their parental origin, but reversible on passage through the germ line. In this chapter, we shall consider the functional properties of imprinted genes, why these genes might have been singled out for the risky strategy of mono-allelic expression, and how imprinting is regulated. We shall look at how imprinted genes affect processes...
Topics
- Animals
- Diabetes Mellitus
- Female
- Gene Expression Regulation, Developmental
- Gene Silencing
- Genomic Imprinting
- Humans
- Male
- Mammals
- Mice
- Pancreas
- Phenotype
- Placenta
- Pregnancy
