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Imprinting of Genes and the Barker Hypothesis

1 Oct 2001

Abstract excerpt

Several common adult diseases appear to be related to impaired fetal growth and this may be caused either by nutritional inadequacies at particular stages of pregnancy or by variation in alleles at specific growth loci. Little is known about the genes involved in the underlying mechanism. This review proposes that at least some of the effects have their origins at imprinted loci, genes that are unusual because...

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Share to Epigenetics and DNA Methylation
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PMID: 11869481
DOI: 10.1375/1369052012632

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