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A human vascular endothelial cell model to study angiogenesis and tumorigenesis

1 Apr 1998

Abstract excerpt

Endothelial cell biology has recently been the subject of considerable interest in thrombosis and cancer research. However, the successful establishment of immortalized human endothelial cells which retain differentiated cell characteristics has been rare. We have successfully established immortalized human umbilical vein endothelial cells (HUVECs) by human papilloma virus (HPV)-16 E6-E7. HPV-16 E6, E7 and E6-E7...

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PMID: 9600354
DOI: 10.1093/carcin/19.4.673

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