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Article

Functional polymorphism in the 5'-UTR of CR2 is associated with susceptibility to nasopharyngeal carcinoma.

Oncology reports - 1 Jul 2013

Fan Qin, He Jun-Fang, Wang Qi-Rui, Cai Hong-Bing, Sun Xue-Gang, Zhou Xin-Xi, Qin Hai-De, Shugart Yin Yao, Jia Wei-Hua

Abstract excerpt

Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) is a squamous cell cancer endemic in Southern China and Southeast Asia. It has been shown that inflammatory and immune responses during EBV infection contribute to the development of NPC. The complement receptor 2 (CR2) gene plays central roles during inflammatory and immune responses and, therefore, is a good candidate susceptibility gene for...

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Identifiers

PMID: 23612877
DOI: 10.3892/or.2013.2421
PMCID: PMC3729234

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