Article
Bone marrow niche and leukemia.
Ernst Schering Foundation symposium proceedings - 1 Jan 2006
Ho A D, Wagner W
Abstract excerpt
Mounting evidence indicates that human cancers may originate from malignant transformation of stem cells. The most convincing proof is found in acute myeloid leukemia, where only a small subset of slowly dividing cells was able to induce transplantable acute myeloid leukemia. Normal hematopoietic stem cells (HSC) are characterized by their unlimited ability to self-renew, give rise to a multitude of cells that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
