Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Normal Stem Cells and Cancer Stem Cells: The Niche Matters

1 May 2006

Abstract excerpt

Scientists have tried for decades to understand cancer development in the context of therapeutic strategies. The realization that cancers may rely on "cancer stem cells" that share the self-renewal feature of normal stem cells has changed the perspective with regard to new approaches for treating the disease. In this review, we propose that one of the differences between normal stem cells and cancer stem cells is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Epigenetics and DNA Methylation
Share to Hedgehog Signaling Pathway Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16651403
DOI: 10.1158/0008-5472.can-05-3986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Normal Stem Cells and Cancer Stem Cells: The Niche MattersPMID 16651403Read ↗

The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?Semantic proximity Read ↗

The cancer stem cell niche—there goes the neighborhood?Semantic proximity Read ↗

Stem Cell Niche in Tissue Homeostasis, Aging and CancerSemantic proximity Read ↗

Stem Cell Niche in Tissue Homeostasis, Aging and CancerSemantic proximity Read ↗

Formation of benign tumors by stem cell deregulationSemantic proximity Read ↗

Mechanisms that mediate stem cell self‐renewal and differentiationSemantic proximity Read ↗

Regulation of self‐renewal in normal and cancer stem cellsSemantic proximity Read ↗

Cancer Stem Cell Niche: The Place to BeSemantic proximity Read ↗

Characteristics of the cancer stem cell niche and therapeutic strategiesSemantic proximity Read ↗

The stem cell niche in health and malignancySemantic proximity Read ↗

An Overview of Concepts for Cancer Stem CellsSemantic proximity Read ↗

New hope for cancer treatment: exploring the distinction between normal adult stem cells and cancer stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.