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Article

In vitro activity of DC-159a, a new broad-spectrum fluoroquinolone, compared with that of other agents against drug-susceptible and -resistant pneumococci.

Antimicrobial agents and chemotherapy - 1 Jan 2008

Clark Catherine, Smith Kathy, Ednie Lois, Bogdanovich Tatiana, Dewasse Bonifacio, McGhee Pamela, Appelbaum Peter C

Abstract excerpt

DC-159a yielded MICs of <or=1 mug/ml against 316 strains of both quinolone-susceptible and -resistant pneumococci (resistance was defined as a levofloxacin MIC >or=4 microg/ml). Although the MICs for DC-159a against quinolone-susceptible pneumococci were a few dilutions higher than those of gemifloxacin, the MICs of these two compounds against 28 quinolone-resistant pneumococci were identical. The DC-159a MICs...

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Identifiers

PMID: 17938189
DOI: 10.1128/AAC.01229-07
PMCID: PMC2223909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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