Article
The level of serum secretory IgA of patients with IgA nephropathy is elevated and associated with pathological phenotypes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 2008
Zhang Jun-jun, Xu Li-xia, Liu Gang, Zhao Ming-hui, Wang Hai-yan
Abstract excerpt
BACKGROUND: Mucosal infection associated episodic macroscopic haematuria is observed in many patients with IgA nephropathy (IgAN), however, the mechanism has not been elucidated. Recent study suggested that secretory IgA (SIgA) might play an important role in the pathogenesis of IgAN. The aim of this study is to investigate the level of serum SIgA and the deposition of SIgA in glomeruli in IgAN patients with...
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