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Article

Association of tumor necrosis factor (TNF) promoter polymorphisms with plasma TNF-α levels and susceptibility to diabetic nephropathy in North Indian population.

Journal of diabetes and its complications - 1 Apr 2015

Gupta Stuti, Mehndiratta Mohit, Kalra Sarathi, Kalra Om P, Shukla Rimi, Gambhir Jasvinder K

Abstract excerpt

AIM: The concept of diabetic nephropathy (DN) as a metabolic disease is now being replaced by chronic low-grade inflammatory disease. Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine which plays an important role in the pathogenesis and clinical outcome of DN. Therefore, this work was planned to evaluate the association of -863C/A (rs1800630) and -1031T/C (rs1799964) polymorphisms in TNF gene...

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Source

Identifiers

PMID: 25704106
DOI: 10.1016/j.jdiacomp.2015.01.002

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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