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Article

Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid.

Chemotherapy - 1 Jan 2007

Escribano I, Rodríguez J C, Llorca B, García-Pachon E, Ruiz M, Royo G

Abstract excerpt

OBJECTIVE: Our aim was to study the influence of efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid. METHODS: We studied the mutations in gyrA and gyrB genes and the influence of efflux pump systems with 2 inhibitors (reserpine and MC 207.110). RESULTS: The effect of the active efflux system on the decrease in sensitivity to ciprofloxacin, moxifloxacin,...

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Source

Identifiers

PMID: 17934259
DOI: 10.1159/000109769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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