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Article

Ofloxacin resistance in Mycobacterium tuberculosis is associated with efflux pump activity independent of resistance pattern and genotype.

Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2014

Sun Zhaogang, Xu Yuhui, Sun Yong, Liu Yi, Zhang Xuxia, Huang Hairong, Li Chuanyou

Abstract excerpt

Drug-resistance to ofloxacin (OFX) in Mycobacterium tuberculosis is due to missense mutations in gyrA and other factors, such as alterations in the activity of drug efflux pumps. In this study, we identified 8 extensively drug resistant tuberculosis (XDR-TB), 40 multidrug resistant TB (MDR-TB), 3...

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Source

Identifiers

PMID: 24940805
DOI: 10.1089/mdr.2013.0171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24940805-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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