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Article

The variability of the mitochondrial genome in human aging: a key for life and death?

The international journal of biochemistry & cell biology - 1 Nov 2002

Rose G, Passarino G, Franceschi C, De Benedictis G

Abstract excerpt

The impressive performance of the research in mitochondrial genetics and human aging in the last decade outlines a new scenery in which the inherited variation of the mitochondrial genome (mtDNA) may play a role in rate and quality of aging. This variation in humans was initially looked at as nearly neutral, and useful just for the reconstruction of human population history. However, recent data suggest that...

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PMID: 12200038
DOI: 10.1016/s1357-2725(02)00042-0

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