Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Critical roles for a genetic code alteration in the evolution of the genus Candida.

The EMBO journal - 31 Oct 2007

Silva Raquel M, Paredes João A, Moura Gabriela R, Manadas Bruno, Lima-Costa Tatiana, Rocha Rita, Miranda Isabel, Gomes Ana C, Koerkamp Marian J G, Perrot Michel, Holstege Frank C P, Boucherie Hélian, Santos Manuel A S

Abstract excerpt

During the last 30 years, several alterations to the standard genetic code have been discovered in various bacterial and eukaryotic species. Sense and nonsense codons have been reassigned or reprogrammed to expand the genetic code to selenocysteine and pyrrolysine. These discoveries highlight unexpected flexibility in the genetic code, but do not elucidate how the organisms survived the proteome chaos generated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida
Share to Genetic Code

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Techniques

Share to Genome, Fungal

Share to Lysine

Share to Nucleic Acid Conformation

Share to Proteomics

Share to Selenocysteine

Source

Open in PubMed Open full text

Identifiers

PMID: 17932489
DOI: 10.1038/sj.emboj.7601876
PMCID: PMC2063480

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Critical roles for a genetic code alteration in the evolution of the genus Candida.PMID 17932489Read ↗

Yeast as a model organism for studying the evolution of non-standard genetic codes.Semantic proximity Read ↗

Selective advantages created by codon ambiguity allowed for the evolution of an alternative genetic code in Candida spp.Semantic proximity Read ↗

A genetic code alteration is a phenotype diversity generator in the human pathogen Candida albicans.Semantic proximity Read ↗

A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicans.Semantic proximity Read ↗

Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification.Semantic proximity Read ↗

[The molecular mechanism of evolution of changes in the genetic code].Semantic proximity Read ↗

Mistranslation: from adaptations to applications.Semantic proximity Read ↗

Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogenSemantic proximity Read ↗

An expanded eukaryotic genetic code.Semantic proximity Read ↗

Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes.Semantic proximity Read ↗

Unity in diversity: lessons from Candida.Semantic proximity Read ↗

Genetic code ambiguity: an unexpected source of proteome innovation and phenotypic diversity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.