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Article

betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development.

Molecular and cellular neurosciences - 1 Jan 2008

Sinha Debasish, Klise Andrew, Sergeev Yuri, Hose Stacey, Bhutto Imran A, Hackler Laszlo, Malpic-Llanos Tanya, Samtani Sonia, Grebe Rhonda, Goldberg Morton F, Hejtmancik J Fielding, Nath Avindra, Zack Donald J, Fariss Robert N, McLeod D Scott, Sundin Olof, Broman Karl W, Lutty Gerard A, Zigler J Samuel

Abstract excerpt

Vascular remodeling is a complex process critical to development of the mature vascular system. Astrocytes are known to be indispensable for initial formation of the retinal vasculature; our studies with the Nuc1 rat provide novel evidence that these cells are also essential in the retinal vascular remodeling process. Nuc1 is a spontaneous mutation in the Sprague-Dawley rat originally characterized by nuclear...

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Identifiers

PMID: 17931883
DOI: 10.1016/j.mcn.2007.08.016
PMCID: PMC4943342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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