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Article

A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish.

Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2007

Liu Jing, Fraser Sherri D, Faloon Patrick W, Rollins Evvi Lynn, Vom Berg Johannes, Starovic-Subota Olivera, Laliberte Angie L, Chen Jau-Nian, Serluca Fabrizio C, Childs Sarah J

Abstract excerpt

The vasculature tailors to the needs of different tissues and organs. Molecular, structural, and functional specializations are observed in different vascular beds, but few genetic models give insight into how these differences arise. We identify a unique cerebrovascular mutation in the zebrafish affecting the integrity of blood vessels supplying the brain. The zebrafish bubblehead (bbh) mutant exhibits...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17573532
DOI: 10.1073/pnas.0700825104
PMCID: PMC1955796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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