Article
Metabolic alterations and shifts in energy allocations are corequisites for the expression of extended longevity genes in Drosophila.
Annals of the New York Academy of Sciences - 1 Apr 2002
Arking Robert, Buck Steven, Hwangbo Dae-Sung, Lane Mark
Abstract excerpt
Evolutionary theories suggest that the expression of extended longevity depends on the organism's ability to shift energy from reproduction to somatic maintenance. New data led us to reexamine our older data and integrate the two into a larger picture of the genetic and metabolic alterations required if the animal is to live long. Our Ra normal-lived control strain can express any one of three different extended...
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