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Article

Different age-specific demographic profiles are generated in the same normal-lived Drosophila strain by different longevity stimuli.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2002

Arking Robert, Novoseltseva Janna, Hwangbo Dae-Sung, Novoseltsev Vassily, Lane Mark

Abstract excerpt

We review the empirical data obtained with our normal-lived Ra control strain of Drosophila and show that this one genome is capable of invoking at least three different responses to external stimuli that induce the animal to express one of three different extended longevity phenotypes, each of which arises from one of three different antagonistic molecular mechanisms of stress resistance. The phenotypes are...

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PMID: 12403794
DOI: 10.1093/gerona/57.11.b390

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