Article
MTHFR polymorphisms as prognostic factors in sporadic colorectal cancer.
Journal of gastrointestinal and liver diseases : JGLD - 1 Sept 2007
Osian Gelu, Procopciuc Lucia, Vlad Liviu
Abstract excerpt
AIM: Theoretically, individuals having at least one mutant allele present a modified activity of the MTHFR enzyme and low methylation, DNA synthesis-repair respectively, which could imply a higher risk of colorectal cancer. The purpose of this study was to investigate the relations of these mutations with the clinico-pathological aspects of colorectal cancer. MATERIAL AND METHOD: The study included 69 patients...
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