Article
GSTM, GSTT and p53 polymorphisms as modifiers of clinical outcome in colorectal cancer.
Anticancer research - 1 Jan 2000
Csejtei Andras, Tibold Antal, Varga Zsuzsa, Koltai Katalin, Ember Agoston, Orsos Zsuzsa, Feher Gergely, Horvath Ors Peter, Ember Istvan, Kiss Istvan
Abstract excerpt
BACKGROUND: Cancer of the colorectal region is the second most frequent cause of death among malignant diseases. The influence of two allelic polymorphisms of GSTM1 and GSTT1, and that of p53 gene codon 72 on colon cancer was investigated. PATIENTS AND METHODS: Intraoperatively removed tissue samples were processed from colorectal cancer patients. Cancer-free human samples were used as matched controls. Samples...
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