The JmjC domain‐containing histone demethylase KDM3A is a positive regulator of the G ₁ /S transition in cancer cells <i>via</i> transcriptional regulation of the <i>HOXA1</i> gene

Abstract excerpt

A number of histone demethylases have been identified and biochemically characterized, yet their biological functions largely remain uncharacterized, particularly in the context of human diseases such as cancer. In this study, we describe important roles for the histone demethylase KDM3A, also known as JMJD1A, in human carcinogenesis. Expression levels of KDM3A were significantly elevated in human bladder...

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