Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.

Human molecular genetics - 15 Apr 2009

Birley Andrew J, James Michael R, Dickson Peter A, Montgomery Grant W, Heath Andrew C, Martin Nicholas G, Whitfield John B

Abstract excerpt

We have previously found that variation in alcohol metabolism in Europeans is linked to the chromosome 4q region containing the ADH gene family. We have now typed 103 single nucleotide polymorphisms (SNPs) across this region to test for allelic associations with variation in blood and breath alcohol concentrations after an alcohol challenge. In vivo alcohol metabolism was modelled with three parameters that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Consumption and Health Effects
Share to Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alcoholism

Share to Lipid metabolism and biosynthesis

Share to Peroxisome Proliferator-Activated Receptors

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 19193628
DOI: 10.1093/hmg/ddp060
PMCID: PMC2664151

Genes

ADH7
ADH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.PMID 19193628Read ↗

Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism.Semantic proximity Read ↗

Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes.Semantic proximity Read ↗

Scanning of genetic effects of alcohol metabolism gene (ADH1B and ADH1C) polymorphisms on the risk of alcoholism.Semantic proximity Read ↗

Genetic time-series analysis identifies a major QTL for in vivo alcohol metabolism not predicted by in vitro studies of structural protein polymorphism at the ADH1B or ADH1C loci.Semantic proximity Read ↗

Associations between ADH gene variants and alcohol phenotypes in Dutch adults.Semantic proximity Read ↗

Alcoholism and alcohol drinking habits predicted from alcohol dehydrogenase genes.Semantic proximity Read ↗

Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample.Semantic proximity Read ↗

Variation in gastric alcohol dehydrogenase and the risk of alcohol dependence.Semantic proximity Read ↗

Genes encoding enzymes involved in ethanol metabolismSemantic proximity Read ↗

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.Semantic proximity Read ↗

Rare ADH variant constellations are specific for alcohol dependence.Semantic proximity Read ↗

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.