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Article

Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophy.

American journal of physiology. Heart and circulatory physiology - 1 Dec 2007

Nakano Noritsugu, Hori Hisae, Abe Minako, Shibata Hiroki, Arimura Takuro, Sasaoka Taishi, Sawabe Motoji, Chida Kouji, Arai Tomio, Nakahara Ken-ichi, Kubo Toru, Sugimoto Ken, Katsuya Tomohiro, Ogihara Toshio, Doi Yoshinori, Izumi Tohru, Kimura Akinori

Abstract excerpt

Elevated wall stress by hypertension induces an adaptive myocardial hypertrophy via releasing prohypertrophic hormones such as angiotensin II. In this study, we investigated the involvement of bone morphogenetic protein-10 (BMP10) in hypertension-induced cardiac hypertrophy. Expression of BMP10 was increased in the hypertrophied ventricles from hypertensive rats. BMP10 localized on cell surface and at...

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Identifiers

PMID: 17921333
DOI: 10.1152/ajpheart.00311.2007

Genes

BMP10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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