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Article

Recently identified colon cancer predispositions: MYH and MSH6 mutations.

Seminars in oncology - 1 Oct 2007

Kastrinos Fay, Syngal Sapna

Abstract excerpt

Single-gene germline mutations conferring a high lifetime risk of colorectal cancer (CRC) account for up to 6% of all CRC cases. The most widely studied monogenic colorectal cancer syndromes include familial adenomatous polyposis (FAP) and Lynch syndrome. However, additional syndromes continue to be defined and new predisposition genes are continuing to be identified. Most recently, MYH-associated polyposis (MAP)...

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Source

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Identifiers

PMID: 17920897
DOI: 10.1053/j.seminoncol.2007.07.005
PMCID: PMC2259279

Genes

MSH6
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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