Hereditary Colorectal Tumors: A Literature Review on MUTYH-Associated Polyposis

doi:10.1155/2017/8693182

Article

Hereditary Colorectal Tumors: A Literature Review on MUTYH-Associated Polyposis

1 Jan 2017

Abstract excerpt

MAP (MUTYH-associated polyposis) is a syndrome, described in 2002, which is associated with colorectal adenomas, with enhanced colorectal carcinogenesis. This review synthesizes the available literature on MAP and outlines its pathogenesis, association with colorectal tumorigenesis, screening, treatment, and the subtle differences between it and its close cousins-FAP and AFAP. The preponderance of data is...

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