Article
Hereditary and familial colon cancer.
Gastroenterology - 1 Jun 2010
Jasperson Kory W, Tuohy Thérèse M, Neklason Deborah W, Burt Randall W
Abstract excerpt
Between 2% to 5% of all colon cancers arise in the setting of well-defined inherited syndromes, including Lynch syndrome, familial adenomatous polyposis, MUTYH-associated polyposis, and certain hamartomatous polyposis conditions. Each is associated with a high risk of colon cancer. In addition to the syndromes, up to one-third of colon cancers exhibit increased familial risk, likely related to inheritance. A...
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