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Article

A pooled analysis of the outcome of prospective colonoscopic surveillance for familial colorectal cancer.

International journal of cancer - 15 Feb 2014

Mesher David, Dove-Edwin Isis, Sasieni Peter, Vasen Hans, Bernstein Inge, Royer-Pokora Brigitte, Holinski-Feder Elke, Lalloo Fiona, Evans D Gareth, Forsberg Anna, Lindblom Annika, Thomas Huw

Abstract excerpt

Surveillance guidelines for the management of familial colorectal cancer (FCC), a dominant family history of colorectal cancer in which the polyposis syndromes and Lynch syndrome have been excluded, are not firmly established. The outcome of colonoscopic surveillance is studied using data from six centers. DNA mismatch repair deficiency was excluded by genetic testing. Families were classified as FCC type X if...

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PMID: 23901040
DOI: 10.1002/ijc.28397

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