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Article

ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2008

Luo Xingguang, Kranzler Henry R, Zuo Lingjun, Zhang Huiping, Wang Shuang, Gelernter Joel

Abstract excerpt

Human personality traits have been closely linked to substance dependence (SD), and are partially genetically determined. Recently, associations between alcohol dehydrogenase 7 (ADH7) and SD have been reported, which led us to investigate the relationship between ADH7 variation and personality traits. We assessed dimensions of the five-factor model of personality and genotyped 4 ADH7 markers and 38 unlinked...

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Source

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Identifiers

PMID: 17918242
DOI: 10.1002/ajmg.b.30589
PMCID: PMC3160628

Genes

ADH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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