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Article

CHRM2 variation predisposes to personality traits of agreeableness and conscientiousness.

Human molecular genetics - 1 Jul 2007

Luo Xingguang, Kranzler Henry R, Zuo Lingjun, Zhang Huiping, Wang Shuang, Gelernter Joel

Abstract excerpt

Personality traits are among the most complex quantitative traits. Certain personality traits have been postulated to be part of the inherited component of substance dependence (SD) risk. Association between the M2 cholinergic receptor gene (CHRM2) and SD has recently been reported and replicated (Wang et al. Hum. Mol. Genet. (2004);13:1903-1911; Luo et al. Hum. Mol. Genet. 2005;14:2421-2434). In this study, we...

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Identifiers

PMID: 17468496
DOI: 10.1093/hmg/ddm104

Genes

CHRM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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