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Human Multipotent Stromal Cells Undergo Sharp Transition from Division to Development in Culture

4 Oct 2007

Abstract excerpt

Human mesenchymal stem cells, or multipotent stromal cells (MSCs), are of interest for clinical therapy, in part because of their capacity for proliferation and differentiation. However, results from clinical trials and in vitro models have been variable, possibly because of MSC heterogeneity and a lack of standardization between MSC in vitro expansion protocols. Here we defined changes in MSCs during expansion...

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PMID: 17916801
DOI: 10.1634/stemcells.2007-0524

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