Article
Transcriptome profiles acquired during cell expansion and licensing validate mesenchymal stromal cell lineage genes
14 Aug 2020
Abstract excerpt
BACKGROUND: Mesenchymal stromal cells (MSCs) are rapidly advancing as commercial therapeutics. However, there are still no adequate tools to validate the identity of MSCs and support standardization of MSC-based products. Currently accepted metrics include cell surface marker profiling and tri-lineage differentiation assays, neither of which is definitive. Transcript profiling represents a cost- and...
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