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Article

Changes in chondrogenic phenotype and gene expression profiles associated with the in vitro expansion of human synovium-derived cells.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Oct 2010

Han Hyuk-Soo, Lee Sahnghoon, Kim Ji Hyun, Seong Sang Cheol, Lee Myung Chul

Abstract excerpt

We undertook this study to characterize changes in the proliferative capacities, chondrogenic phenotypes, and gene expression profiles of human synovium-derived progenitor cells from osteoarthritic patients during in vitro expansion. Cells isolated from osteoarthritic synovia were cultured, and growth rates during serial passages were evaluated. Surface molecule expressions were determined by flow cytometry and...

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PMID: 20225285
DOI: 10.1002/jor.21129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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