Article
The mutations in ISDR of NS5A gene are not associated with response to interferon treatment in Turkish patients with chronic hepatitis C virus genotype 1b infection.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Mar 2004
Aslan Nuray, Bozdayi A Mithat, Cetinkaya Hülya, Sarioğlu Mustafa, Türkay Cansel, Bozkaya Hakan, Karayalçin Selim, Yurtaydin Cihan, Uzunalimoğlu Ozden
Abstract excerpt
BACKGROUND/AIMS: A significant association between variations in amino acid sequences resides between 2209-2248 nucleotides of HCV non-structural 5A (NS5A) gene, and response to interferon treatment has been proposed. The aim of this study was to determine whether the amino acid sequence changes in ISDR could be correlated to response to alpha interferon treatment in Turkish patients infected with HCV genotypes...
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