Article
Meta-analysis of mutations in the NS5A gene and hepatitis C virus resistance to interferon therapy: uniting discordant conclusions.
Antiviral therapy - 1 Apr 2004
Schinkel Janke, Spaan Willy J M, Kroes Aloys C M
Abstract excerpt
BACKGROUND: Hepatitis C virus genotype 1B responds poorly to treatment with interferon, in contrast to the more interferon-sensitive genotypes 2 and 3. Studies on combination therapy regimens with PEG-interferon and ribavirin report sustained response rates that generally do not exceed 50%, in co...
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