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Article

Histone chaperones regulate histone exchange during transcription.

The EMBO journal - 31 Oct 2007

Kim Hye-Jin, Seol Ja-Hwan, Han Jeung-Whan, Youn Hong-Duk, Cho Eun-Jung

Abstract excerpt

Transcription by RNA polymerase II is accompanied by dynamic changes in chromatin, including the eviction/deposition of nucleosomes or the covalent modification of histone subunits. This study examined the role of the histone H3/H4 chaperones, Asf1 and HIR, in histone mobility during transcription, with particular focus on the histone exchange pathway, using a dual histone expression system. The results showed...

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Identifiers

PMID: 17914459
DOI: 10.1038/sj.emboj.7601870
PMCID: PMC2063486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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