Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types

1 Oct 2007

Abstract excerpt

The GATA-4 and GATA-5 transcription factors are increasingly recognized as playing a role in carcinogenesis of human tumors derived of endodermal and mesodermal origin. The pancreas is derived from endodermal tissues suggesting GATA-4 and GATA-5 gene methylation may play a critical role in the biology of human pancreatic cancer as well. We investigated GATA-4 and -5 by methylation-specific PCR (MSP) in normal and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Tracheal and airway disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17912029
DOI: 10.4161/cbt.6.10.4708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor typesPMID 17912029Read ↗

Hypermethylation of the GATA gene family in esophageal cancerSemantic proximity Read ↗

GATA6 in pancreatic cancer initiation and progressionSemantic proximity Read ↗

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancerSemantic proximity Read ↗

GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1Semantic proximity Read ↗

GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Hypermethylation of the GATA Genes in Lung CancerSemantic proximity Read ↗

TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional SubtypesSemantic proximity Read ↗

Genomic Profiling Identifies GATA6 as a Candidate Oncogene Amplified in Pancreatobiliary CancerSemantic proximity Read ↗

Methylation-Mediated Silencing of GATA5 Gene Suppresses Cholangiocarcinoma Cell Proliferation and MetastasisSemantic proximity Read ↗

GATA Transcription Factors and CancerSemantic proximity Read ↗

Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.