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Article

Hypermethylation of the GATA Genes in Lung Cancer

1 Dec 2004

Abstract excerpt

PURPOSE: In lung cancer, DNA hypermethylation is known to be a common event. EXPERIMENTAL DESIGN: Gene expression and methylation status of GATA-4, GATA-5, and GATA-6 were analyzed with cell lines and primary human lung cancers. Methylation profiles of primary lung cancers were analyzed and correlated with clinical as well as histopathological data. RESULTS: Complete methylation was detected by...

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PMID: 15585625
DOI: 10.1158/1078-0432.ccr-04-1140

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