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Article

Individual responses to novelty are associated with differences in behavioral and neurochemical profiles.

Behavioural brain research - 5 Mar 2008

Antoniou K, Papathanasiou G, Papalexi E, Hyphantis T, Nomikos G G, Spyraki C, Papadopoulou-Daifoti Z

Abstract excerpt

Experimental animals can be differentiated on the basis of their horizontal or vertical activity to high responders (HR) and low responders (LR) upon exposure to a novel environment. These individual differences have been associated with behavioral and neurobiological differences in a number of experimental procedures used for studying sensitivity to psychostimulants, anxiety, depression, and cognitive function....

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PMID: 18036673
DOI: 10.1016/j.bbr.2007.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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