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Article

Enhanced recognition memory following glycine transporter 1 deletion in forebrain neurons.

Behavioral neuroscience - 1 Oct 2007

Singer Philipp, Boison Detlev, Möhler Hanns, Feldon Joram, Yee Benjamin K

Abstract excerpt

Selective deletion of glycine transporter 1 (GlyT1) in forebrain neurons enhances N-methyl-D-aspartate receptor (NMDAR)-dependent neurotransmission and facilitates associative learning. These effects are attributable to increases in extracellular glycine availability in forebrain neurons due to reduced glycine re-uptake. Using a forebrain- and neuron-specific GlyT1-knockout mouse line (CamKIIalphaCre;...

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Identifiers

PMID: 17907814
DOI: 10.1037/0735-7044.121.5.815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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