Article
Neovascularization induced by porous collagen scaffold implanted on intact and cryoinjured rat hearts.
Biomaterials - 1 Dec 2007
Callegari Andrea, Bollini Sveva, Iop Laura, Chiavegato Angela, Torregrossa Gianluca, Pozzobon Michela, Gerosa Gino, De Coppi Paolo, Elvassore Nicola, Sartore Saverio
Abstract excerpt
The potential of collagen scaffolds for promoting angiogenesis/arteriogenesis was studied in vivo by implantation on healthy or cryoinjured left ventricles of rats up to 60 days post-injury. Blood vessels content and extra-vascular cell infiltration were evaluated within the collagen scaffold, the cryoinjured areas, and the "border zones" of the myocardium facing the cryoinjured zones. The collagen cardiac...
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