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Article

Multiple cryoinjuries modulate the efficiency of zebrafish heart regeneration.

Scientific reports - 14 Jul 2020

Bise Thomas, Sallin Pauline, Pfefferli Catherine, Jaźwińska Anna

Abstract excerpt

Zebrafish can regenerate their damaged hearts throughout their lifespan. It is, however, unknown, whether regeneration remains effective when challenged with successive cycles of cardiac damage in the same animals. Here, we assessed ventricular restoration after two, three and six cryoinjuries interspaced by recovery periods. Using transgenic cell-lineage tracing analysis, we demonstrated that the second...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32665622
DOI: 10.1038/s41598-020-68200-1
PMCID: PMC7360767

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