Article
Epicardial delivery of VEGF and cardiac stem cells guided by 3-dimensional PLLA mat enhancing cardiac regeneration and angiogenesis in acute myocardial infarction.
Journal of controlled release : official journal of the Controlled Release Society - 10 May 2015
Chung Hye-Jin, Kim Jong-Tae, Kim Hee-Jung, Kyung Hei-Won, Katila Pramila, Lee Jeong-Han, Yang Tae-Hyun, Yang Young-Il, Lee Seung-Jin
Abstract excerpt
Congestive heart failure is mostly resulted in a consequence of the limited myocardial regeneration capacity after acute myocardial infarction. Targeted delivery of proangiogenic factors and/or stem cells to the ischemic myocardium is a promising strategy for enhancing their local and sustained therapeutic effects. Herein, we designed an epicardial delivery system of vascular endothelial growth factor (VEGF) and...
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