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Article

Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity.

Annals of human genetics - 1 Jan 2008

Sanghera Dharambir K, Manzi Susan, Minster Ryan L, Shaw Penny, Kao Amy, Bontempo Franklin, Kamboh M Ilyas

Abstract excerpt

Low serum paraoxonase1 (PON1) activity determined by paraoxon substrate is associated with coronary heart disease (CHD), diabetes and systemic lupus erythematosus (SLE) risk. In this investigation, we have examined the role of genetic variation in the PON3 gene in relation to PON1 activity and SLE risk in a biracial sample comprising 377 SLE patients and 482 controls from US whites and blacks. We genotyped six...

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Source

Identifiers

PMID: 17900266
DOI: 10.1111/j.1469-1809.2007.00400.x

Genes

PON1
PON3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity.PMID 17900266Read ↗

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