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Article

Metabolism of antidepressant and neuroleptic drugs by cytochrome p450s: clinical and interethnic aspects.

Clinical pharmacology and therapeutics - 1 Nov 2007

Bertilsson L

Abstract excerpt

Early after the introduction of the classical tricyclic antidepressants and neuroleptics, it was shown that the plasma concentrations of these drugs varied between patients given the same dose. This variation is to a major extent due to the variation in the activity of cytochrome P450 (CYP) enzym...

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Identifiers

PMID: 17898711
DOI: 10.1038/sj.clpt.6100358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17898711-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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