Pharmacogenetics and drug metabolism of newer antidepressant agents.

Article

Pharmacogenetics and drug metabolism of newer antidepressant agents.

The Journal of clinical psychiatry - 1 Dec 1994

DeVane C L

Abstract excerpt

A wide variety of drugs are metabolized by the human cytochrome P450 system, including antidepressants such as tricyclic antidepressants and serotonin selective reuptake inhibitors (SSRIs). Each P450 isoenzyme is the product of a separate gene; a number of genes have multiple alleles that result...

Topics

Alleles
Antidepressive Agents
Antidepressive Agents, Tricyclic
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System
Depressive Disorder
Drug Interactions
Humans
Pharmacogenetics
Polymorphism, Genetic
Selective Serotonin Reuptake Inhibitors

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